Zofran and pregnancy
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Zofran’s Heart Risks Extend into Early Childhood Development

Heart risks associated with the use of anti-nausea medication Zofran (ondansetron) by pregnant mothers aren’t solely limited to unborn babies − infants and small children remain at risk for potentially fatal heart-related side effects of Zofran as well. According to the findings of a study published in the journal Pediatric Emergency Care, prescribing Zofran for nausea and vomiting may prove lethal for young children, according to doctors from the Lehigh Valley Health Network, whose research uncovered two fatalities associated with this dangerous drug. One healthy 10-year-old, who was prescribed Zofran for the stomach flu, later passed away from abnormal heart rate.  In another such example, a two-month-old infant who was given Zofran (ondansetron) died from rapid heart rhythm and contraction problems in the cardiac muscles. Zofran (ondansetron) has been widely connected to congenital heart defects, as well as other birth defects like cleft palate, in children after their mothers were prescribed the drug for morning sickness during pregnancy. Zofran (ondansetron) has only been approved by the FDA for use in cancer chemotherapy, radiation, or organ replacement surgery patients, but has been prescribed for off-label purposes without warning of the serious risks to children.

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